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http://marvel.wikia.com/wiki/Wade_Wilson_(Earth-90211)

In the 1980s, Wade Wilson, as Deadpool, was hired by Galactus to kill the Beyonder in retaliation for merging M.O.D.O.K. to Galactus's rear end in exchange for the Continuity Cube. Armed with the Recton Expungifier, the only weapon which could kill the Beyonder, Wilson traced his target to a nightclub and was subsequently enticed into the Beyonder's partying lifestyle - and in the process gained Jheri curls.

While hanging out with the Beyonder in a flying limousine, Spider-Man broke into the car and demanded the Beyonder remove the Symbiote costume from him. Spider-Man was then shot out of the limousine by Beyonder's driver and singer Bobby Oceanic. The Symbiote departed Peter Parker's body and merged with Wilson, and the two became "Venompool".

After years of partying, the Beyonder grew tired of all the fun, and returned Venompool to the world. Venompool was snapped out of Beyonder's magic and tried to resume his contract to kill Beyonder, but then realized he had pawned the Recton Expungifier. Venompool got himself clean by kidnapping and selling a drunken Tony Stark to A.I.M.. He used his money to start his life over until he finally spent all his money away and deciding to become a real hero. Unfortunately, Venompool couldn't apply to become a member any famous superhero teams such as the Fantastic Four, the Avengers, or the Defenders due to possessing the now unpopular Jheri curls. Knowing what he had to do, Venompool tried to remove his Jheri curls by using a bell tower. The ringing of the bells freed him from the Jheri curls.

Despite being rid of the Jheri curls, Venompool's actions as a "hero", the slaughtering of small time crooks, only left mindless violence in his wake. Venompool was once again looked down and frowned upon by society. Venompool was advised by a passing police officer to entering the Secret Wars, a series of fights between heroes and underdeveloped villains, in order to boost his recognition. Venompool was criticized by the Sentry, one of the contenders, for not "getting" superheroes. He then left the Secret Wars to find another way to be significant.

Venompool went back to where he pawned the Recton Expungifier and bought the gun back to resume killing the Beyonder. He then made a fake phone call and told Beyonder that he was throwing a gala event celebrating the Beyonder's life in his apartment. Beyonder agreed to make an appearance and Venompool waited for his arrival. The Beyonder arrived with Venompool's archnemesis, Carnage Curl, a female offshoot of his symbiote-sentient Jheri curls. Venompool engaged Carnage Curl and Beyonder on the Hairy Spranger talk show. During the show, Venompool learned to his shock that Carnage Curl was pregnant which led to a surprise guest from Galactus who revealed that he was responsible for impregnating Carnage Curl and then began to fight with Beyonder, causing Earth to be destroyed. Venompool, however, survived and having enough of Galactus and Beyonder, erased them from existence with the Recton Expungifier and saving the Earth.

Venompool was hailed as a hero and gained the recognition he deserved. Although he had become very relevant, he felt that something was still missing. While being interviewed during the premiere of his movie, he noticed Thor was gaining admiration. This made Venompool realize that other people were also being admired so he decided to wipe out anyone who was appreciated for their heroic deeds. Over the next year, Venompool killed every hero and villain, leaving only the more attractive ones alive for adoration purposes. He became the world's only, and thus most important, superhero. He was covered exclusively by the media and his adventures were more significant than any hero's had ever been. Everything he did had a ripple effect in the world where he really, really mattered. Unfortunately, he didn't handle the success with grace. Instead, it was an opportunity to decry all those who opposed him along the way to becoming king of the world. He soon gave in to his own ego, fueled by his long past rejection, and a desperate insecurity that no success could quell. But still, with all the power he had, he realized he was empty and nothing made him feel like the success he worked so hard to achieve.

Venompool underwent therapy by Doc Samson, who explained to Venompool that his problems were the result of the Beyonder's rejection which caused Venompool's inner state to defend himself from the world with a wall of arrogance and ego. As a result, it turned this inner defense mechanism against the world. Samson concluded that it was common for him and other people who felt persecuted to be blind to the reality that he was just a jerk who no one wanted around. Venompool killed Samson, but Samson's comment led Venompool the startling revelation that he needed to grow and evolve as a human, learn from his mistakes and become a better person for its own sake, even when no one was watching. But unfortunately, his true self was an "unredeemable ass". Instead of doing what he should have done, Venompool erased himself and the universe with the Recton Expungifier.

He apparently survived the destruction of his universe and was later seen recruited by Dreadpool to root out the remaining members of the Deadpool Corps. [1]

He was killed in the Multiversal Deadpool war.[2]
Powers and Abilities
Powers
Seemingly those of Wade Wilson of Earth-616 plus those of Venom of Earth-616.

Paraphernalia
Equipment
Thor's hammer, Captain America's Shield

http://marvel.wikia.com/wiki/Earth-10011

A universe where "death was defeated", the Cancerverse is a reality where nothing dies and life has expanded exponentially, resulting in a universe-wide living corpse. Eternal life fueled by the unseen "many-angled ones", every living being in this universe has seemingly been corrupted and turned to their servitude.

Following the launching of the T-Bomb by the Inhumans of Earth-616 and its subsequent detonation during a battle between that universe's Black Bolt and Vulcan, a breach, known as the Fault, was formed in Earth-616, creating a bridge to this corrupted universe. Several expeditions by Earth-616 entities have led to numerous encounters with the Cancerverse entities, including that reality's Avengers (known as the "Revengers") and X-Men.

Upon discovering the vast room to expand in this universe, the forces of the Cancerverse have launched a campaign to invade Earth-616 and rid it of the abstract entity and very concept of Death.

http://marvel.wikia.com/wiki/Death_(Earth-616)

Mortal beings have always strove to make sense of and control their surroundings. This tendency leads to anthropomorphism, the assignment of mortal motivations to impersonal processes or forces. Personifying these forces creates the expectation that communication with them, and thus influence over them, is possible. Traditionally, ordinary mortals have little or no success in swaying Death once it selects a victim.

This same Mistress Death formed an attachment to Deadpool, whose curse is to be unable to die. These star-crossed lovers can therefore never be together.

When Thanos was brought back to life by the Universal Church of Truth, Death didn't interfere, since she knew Thanos would be vital in stopping the inhabitants of the Cancerverse from conquering Earth-616 and thus eliminating death. She couldn't enter the Cancerverse until Thanos was almost killed by the dark version of Captain Marvel, but when she did, she immediately devastated the Cancerverse, killing the dark Captain Marvel and every other being in the deathless universe. Thanos, however, remained alive, and Death, for some reason, ignored him yet again.[citation needed]

During Wolverine's loss of his healing factor, he became vulnerable. He decided to rediscover his martial arts by training with Iron Fist and Shang-Chi and the three of them went to Itsukushima Island. They battled Sabretooth's Hand Ninjas.[3] After Logan encountered Death, she helps him accept his unavoidable death.

Thanos, in an effort to keep Deadpool away from his beloved Death, cursed him never to die. However, the embodiment of Death had also been kidnapped by Eternity, meaning nothing else in the universe could die either, causing untold chaos throughout the universe. When Deadpool, believing Thanos responsible, arrived on Thanos' ship to defeat him, Thanos rescinded his curse, turning Deadpool into the only mortal creature in the universe, then killed him.[5]

However, upon realizing that Death would only speak to Wade, Thanos resurrected him in order to save her.[5] When the pair managed to travel to Eternity's Realm and encounter him personally, Thanos attacked mercilessly, blaming Eternity for all of his life's ills. Wilson, realizing that this was what Death wanted all along, attacked Thanos and was possessed by the Uni-Power, giving Deadpool the powers of Captain Universe. Using those powers, Deadpool and Thanos fought on equal ground, but Deadpool's speech during the fight convinced Death of the validity of life's existence and caused Mistress Death to whisk Thanos away, for a later purpose and to return to her own, restoring mortality to the universe.

***

Real estate agent Arthur Douglas, his wife Yvette, and daughter Heather, were driving across the Mojave Desert from Las Vegas to Los Angeles when a spaceship carrying the mad Titan named Thanos passed overhead on a surveillance mission to Earth. Wishing to keep his existence a secret, Thanos destroyed the automobile in case its passengers had seen his ship, and then landed to make certain they were dead. Satisfied that they were, Thanos left. Unknown to the Titan, his father Mentor had been monitoring his activities on Earth to examine his son's latest handiwork. Mentor discovered that Heather Douglas was still alive, and took her back to Titan to be raised. She later returned to Earth as Moondragon.

***

Before all was, I was. Before time was, I waited. I fed on the screaming souls of the universes. I drank the spoiled milk of dead stars. I am the emptiness outside all understanding. I am Shuma-Gorath.
-- Shuma-Gorath

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The Last Laugh